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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
3.5 DPC

29 matching records from 29 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gata6  GATA binding protein 6  
Results  Reference
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:330642 Andreu MJ, Alvarez-Franco A, Portela M, Gimenez-Llorente D, Cuadrado A, Badia-Careaga C, Tiana M, Losada A, Manzanares M, Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF. Cell Rep. 2022 Oct 18;41(3):111501
1J:333947 Athanasouli P, Balli M, De Jaime-Soguero A, Boel A, Papanikolaou S, van der Veer BK, Janiszewski A, Vanhessche T, Francis A, El Laithy Y, Nigro AL, Aulicino F, Koh KP, Pasque V, Cosma MP, Verfaillie C, Zwijsen A, Heindryckx B, Nikolaou C, Lluis F, The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency. Nat Commun. 2023 Mar 3;14(1):1210
1J:293567 Azami T, Bassalert C, Allegre N, Valverde Estrella L, Pouchin P, Ema M, Chazaud C, Regulation of the ERK signalling pathway in the developing mouse blastocyst. Development. 2019 Jul 25;146(14):dev177139
1*J:217512 Bessonnard S, De Mot L, Gonze D, Barriol M, Dennis C, Goldbeter A, Dupont G, Chazaud C, Gata6, Nanog and Erk signaling control cell fate in the inner cell mass through a tristable regulatory network. Development. 2014 Oct;141(19):3637-48
1J:342647 Chakraborty S, Kopitchinski N, Zuo Z, Eraso A, Awasthi P, Chari R, Mitra A, Tobias IC, Moorthy SD, Dale RK, Mitchell JA, Petros TJ, Rocha PP, Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nat Genet. 2023 Feb;55(2):280-290
1J:108748 Chazaud C, Yamanaka Y, Pawson T, Rossant J, Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell. 2006 May;10(5):615-24
1*J:331055 Chousal JN, Sohni A, Vitting-Seerup K, Cho K, Kim M, Tan K, Porse B, Wilkinson MF, Cook-Andersen H, Progression of the pluripotent epiblast depends upon the NMD factor UPF2. Development. 2022 Nov 1;149(21):dev200764
1J:323014 Chrysanthou S, Tang Q, Lee J, Taylor SJ, Zhao Y, Steidl U, Zheng D, Dawlaty MM, The DNA dioxygenase Tet1 regulates H3K27 modification and embryonic stem cell biology independent of its catalytic activity. Nucleic Acids Res. 2022 Apr 8;50(6):3169-3189
1J:289553 Fischer SC, Corujo-Simon E, Lilao-Garzon J, Stelzer EHK, Munoz-Descalzo S, The transition from local to global patterns governs the differentiation of mouse blastocysts. PLoS One. 2020;15(5):e0233030
1J:338267 Goissis MD, Bradshaw B, Posfai E, Rossant J, Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo. PLoS One. 2023;18(7):e0279515
1J:240535 Goolam M, Zernicka-Goetz M, The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo. Development. 2017 Apr 15;144(8):1450-1461
1J:241994 Kang M, Garg V, Hadjantonakis AK, Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2. Dev Cell. 2017 Jun 05;41(5):496-510.e5
1*J:191065 Kang M, Piliszek A, Artus J, Hadjantonakis AK, FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development. 2013 Jan;140(2):267-79
1*J:203997 Krawchuk D, Honma-Yamanaka N, Anani S, Yamanaka Y, FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst. Dev Biol. 2013 Dec 1;384(1):65-71
1J:208425 Le Bin GC, Munoz-Descalzo S, Kurowski A, Leitch H, Lou X, Mansfield W, Etienne-Dumeau C, Grabole N, Mulas C, Niwa H, Hadjantonakis AK, Nichols J, Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development. 2014 Mar;141(5):1001-10
1J:344248 Lilao-Garzon J, Brito-Casillas Y, Quesada-Canales O, Wagner AM, Munoz-Descalzo S, Maternal age, obesity and hyperglycaemia are associated with a delay in preimplantation embryo development in mouse. Reproduction. 2023 Sep 1;166(3):235-245
1J:260470 Meng Y, Moore R, Tao W, Smith ER, Tse JD, Caslini C, Xu XX, GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm. Dev Biol. 2018 Apr 1;436(1):55-65
1J:241560 Molotkov A, Mazot P, Brewer JR, Cinalli RM, Soriano P, Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. Dev Cell. 2017 Jun 05;41(5):511-526.e4
1J:283357 Nowotschin S, Setty M, Kuo YY, Liu V, Garg V, Sharma R, Simon CS, Saiz N, Gardner R, Boutet SC, Church DM, Hoodless PA, Hadjantonakis AK, Pe'er D, The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. 2019 May;569(7756):361-367
1*J:138816 Plusa B, Piliszek A, Frankenberg S, Artus J, Hadjantonakis AK, Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development. 2008 Sep;135(18):3081-91
1J:331143 Sathyanarayanan A, Ing-Simmons E, Chen R, Jeong HW, Ozguldez HO, Fan R, Duethorn B, Kim KP, Kim YS, Stehling M, Brinkmann H, Scholer HR, Adams RH, Vaquerizas JM, Bedzhov I, Early developmental plasticity enables the induction of an intermediate extraembryonic cell state. Sci Adv. 2022 Nov 4;8(44):eabl9583
1J:213580 Schrode N, Saiz N, Di Talia S, Hadjantonakis AK, GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell. 2014 May 27;29(4):454-67
1*J:268273 Simon CS, Zhang L, Wu T, Cai W, Saiz N, Nowotschin S, Cai CL, Hadjantonakis AK, A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse. Biol Open. 2018 Dec 10;7(12):bio036517
1*J:312380 Sun-Wada GH, Tabata H, Wada Y, Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm. Sci Rep. 2021 Sep 29;11(1):19355
1*J:326575 Tsume-Kajioka M, Kimura-Yoshida C, Mochida K, Ueda Y, Matsuo I, BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos. BMC Biol. 2022 Mar 9;20(1):64
1J:171449 Williams LH, Kalantry S, Starmer J, Magnuson T, Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57
1J:342639 Xie G, Lee JE, Senft AD, Park YK, Jang Y, Chakraborty S, Thompson JJ, McKernan K, Liu C, Macfarlan TS, Rocha PP, Peng W, Ge K, MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner. Nat Genet. 2023 Apr;55(4):693-705
1*J:259707 Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z, Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice. Nat Commun. 2018 Mar 28;9(1):1261

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory